Bruker's scimaX MRMS is a state-of-the-art mass spectrometry instrument with a 7 Tesla magnet, equipped with a dual ESI and MALDI source. This mass spectrometer is characterized by its high mass resolution and accuracy. In addition, the scimaX offers the possibility to perform MALDI imaging with a lateral resolution of down to 10 µm, which enables detailed spatial mapping of molecular distributions. This device helps us to push the boundaries of our research, especially in areas that require extremely high mass accuracy for molecular identification, and is invaluable when analyzing complex samples.

This instrument is a two-stage vacuum MALDI reflectron time-of-flight mass spectrometer with low energy acceptance and a grounded gas collision cell (E_LAB = 8 keV, Ar). A LIFT cell enables the detection of all productions in a single laser shot during a CID experiment (active precursor ion suppression). Sophisticated software supports the acquisition and visualization of high-quality imaging mass spectrometric data from various biological materials.

The SYNAPT G2 HDMS from Waters is an advanced mass spectrometer known for its sophisticated analytical capabilities. The instrument not only utilizes ion mobility separation, but also has an integrated trap and transfer cell that enables the fragmentation of ions. This capability is crucial for in-depth structural analysis of molecules, providing valuable insights into their composition. In addition to conventional mass spectrometry, the SYNAPT G2 HDMS utilizes high-resolution mass spectrometry (HDMS) technology, which ensures accurate mass measurements and excellent resolution for precise identification and quantification of different molecules.

The instrument's triwave ion mobility cell adds an extra dimension of separation based on molecule size and shape, increasing its versatility in analyzing a wide range of samples, from small analytes to large biomolecules. The SYNAPT G2 HDMS is ideal for various research areas, including proteomics, metabolomics and pharmaceutical applications. Its time-of-flight (TOF) analyzer ensures fast and accurate mass determination, contributing to efficient and reliable data acquisition. In particular, the fragmentation capability of the trap and transfer cell increases the usefulness of the device for structure elucidation.

In addition, the SYNAPT G2 HDMS offers flexibility as it can be operated in both MALDI and ESI mode. This dual-mode operation extends the applicability of the instrument and allows it to be adapted to different sample types and experimental requirements. With its intuitive user interface and customizable features, researchers can benefit from the exceptional sensitivity, selectivity and versatility of the SYNAPT G2 HDMS, making it an invaluable tool for the advancement of analytical chemistry.

This instrument is a hybrid tandem quadrupole/double-stage reflectron time-of-flight mass spectrometer that can be equipped with a dual-jet ESI source or alternatively with a multimode (MMI) ion source (ESI and APCI combined). The collision quadrupole can be operated up to E_LAB = 100 eV with nitrogen as collision gas (alternatively: Ar). Integrated LC/MS software is available for sample analysis down to very low flow rates. With the dual-jet ESI source (sample and reference sprayers are separate), high-resolution, accurate mass data with an accuracy of down to 1 ppm or even lower (MS and MS/MS mode) can be obtained.

This device is a high vacuum source MALDI Reflectron time-of-flight mass spectrometer with gas collision cell (E_LAB = 20 keV, He). Tandem-TOF experiments are possible. Software is also available that enables imaging mass spectrometry and visualization.

The Shimadzu MALDI-8030 is an advanced linear benchtop mass spectrometer characterized by high throughput. Due to its high sensitivity, it can be used for the detection of various analytes, from peptides to small molecules. In addition, the MALDI-8030 is characterized by its compact design, making it suitable for laboratories with limited space without compromising analytical performance. The fast data acquisition contributes to a more efficient workflow and enables samples to be analyzed quickly and reliably. The versatility of the instrument extends to the analysis of a wide range of sample types, including tissue sections, biological fluids and polymers, making it a versatile choice for researchers across different disciplines. The robustness and reliability of the MALDI-8030 make it an indispensable tool for studies that require rapid and qualitative insights into complex molecular compositions. The advanced software facilitates data interpretation and makes it easier for researchers to extract meaningful information from their analyses. The device's user-friendly interface facilitates access for both experienced and inexperienced researchers.