We published our , opens an external URL in a new window, opens an external URL in a new windowstory on the 3D topography of the Immunological Synapse, opens an external URL in a new window, opens an external URL in a new window in Nano Letters. Here, Lukas used a 3D single molecule localization microscopy technique to localize T-cell receptors in the Immunological synapse with a precision below 15 nm. These findings reveal the importance of the T cell topography in the process of T cell activation.